SABA Overuse in Russia – Burden and Possible Causes: An Analysis of the Russian Population in the SABINA III (SABA use IN Asthma) Study
Sergey Avdeev,1 Nikolay Voznesenskiy,2 Marina Boldina,3 Galina Ignatova,4 Natalya Kostina,5 Amirzhan Kulbaisov,6 Igor Leshchenko,7 Maarten JHI Beekman8 1Department of Pulmonology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; 2National Medical Research Center for Pulmonology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; 3Department of Therapy and Cardiology, Privolzhsky Research Medical University, Nizhny Novgorod, Russia; 4Department of Therapy and Postgraduate Education, South Ural State Medical Univer... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2022 |
Reihe/Periodikum: | Journal of Asthma and Allergy, Vol Volume 15, Pp 371-379 (2022) |
Verlag/Hrsg.: |
Dove Medical Press
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Schlagwörter: | bronchial asthma / asthma control / short-acting β2-agonists / saba overuse / over-the-counter use / Immunologic diseases. Allergy / RC581-607 |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27248846 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://doaj.org/article/98e5d33be55044e495400e958ee166ce |
Sergey Avdeev,1 Nikolay Voznesenskiy,2 Marina Boldina,3 Galina Ignatova,4 Natalya Kostina,5 Amirzhan Kulbaisov,6 Igor Leshchenko,7 Maarten JHI Beekman8 1Department of Pulmonology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; 2National Medical Research Center for Pulmonology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; 3Department of Therapy and Cardiology, Privolzhsky Research Medical University, Nizhny Novgorod, Russia; 4Department of Therapy and Postgraduate Education, South Ural State Medical University, Chelyabinsk, Russia; 5Pulmonology Department, Voronezh Regional Clinical Hospital No 1, Voronezh, Russia; 6Pulmonology Department, Orenburg Regional Hospital No 2, Orenburg, Russia; 7Department of Phthisiatry and Pulmonology, Ural State Medical University, Ekaterinburg, Russia; 8LLC AstraZeneca, The Hague, The NetherlandsCorrespondence: Sergey Avdeev, Email serg_avdeev@list.ruBackground: Short-acting β 2-agonists (SABA) overuse is associated with asthma morbidity and mortality. The SABA use IN Asthma (SABINA) program aimed to describe the global use of SABA in patients with asthma. SABINA III study was a cross-sectional study covering 24 countries.Methods: We performed statistical analysis of the Russian population (618 patients recruited in 12 centers) from the SABINA III study. In this study in patients aged ≥ 12 years, data on disease characteristics and asthma treatments were collected using real-time electronic case report forms. Patients were classified by asthma severity and control according to the 2017 GINA. All variables (asthma severity and control, number of severe exacerbations, SABA and other medications use) were analyzed descriptively only, no hypothesis was tested.Results: Majority of the study population consisted of patients with moderate/severe asthma (78.5%), while mild asthma was seen in 21.5%. Asthma was uncontrolled in 36.1% of patients and partly controlled in 33.5%. More than 80% of patients ...