A method to study the effect of bronchodilators on smoke retention in COPD patients: study protocol for a randomized controlled trial
BACKGROUND Chronic obstructive pulmonary disease (COPD) is a common disease, associated with cardiovascular disease. Many patients use (long-acting) bronchodilators, whilst they continue smoking alongside. We hypothesised an interaction between bronchodilators and smoking that enhances smoke exposure, and hence cardiovascular disease. In this paper, we report our study protocol that explores the fundamental interaction, i.e. smoke retention. METHOD The design consists of a double-blinded, placebo-controlled, randomised crossover trial, in which 40 COPD patients smoke cigarettes during both und... Mehr ...
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Dokumenttyp: | Journal article |
Verlag/Hrsg.: |
BioMed Central
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Schlagwörter: | administration / inhalation / breath tests / bronchodilator agents / cardiovascular diseases / cross-over studies / double-blind method / humans / inhalation exposure / lung / netherlands / pulmonary disease / chronic obstructive / questionnaires / respiratory function tests / risk assessment / risk factors / smoking / research design |
Sprache: | unknown |
Permalink: | https://search.fid-benelux.de/Record/base-27238936 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://hdl.handle.net/1885/95209 |