Adipocytokine plasma concentrations reflect influence of inflammation but not body mass index ( BMI) on clinical outcomes of COVID‐19 patients: A prospective observational study from the Netherlands

Summary Obesity is recognized as a risk factor for adverse outcome in COVID‐19, but the molecular mechanisms underlying this relationship remain unknown. Adipose tissue functions as an endocrine organ by secreting multiple pro‐inflammatory and anti‐inflammatory factors, known as adipocytokines, which could be involved in COVID‐19 severity. We explored the role of adipocytokines in COVID‐19 and its association with BMI, clinical outcome, and inflammation. This is an observational study in 195 hospitalized COVID‐19 patients. Serial plasma concentrations of the adipocytokines leptin, adiponectin,... Mehr ...