Childhood trauma and LPS-stimulated inflammation in adulthood:Results from the Netherlands Study of Depression and Anxiety
Background: Childhood trauma (CT) is robustly associated with psychiatric disorders including major depressive and anxiety disorders across the life span. The innate immune system may play a role in the relation between CT and stress-related psychopathology. However, whether CT influences the innate production capacity of cytokine levels following ex vivo stimulation by lipopolysaccharide (LPS), is currently unknown. Methods: Using data from the Netherlands Study of Depression and Anxiety (NESDA, n=1237), we examined whether CT (emotional neglect, emotional, physical, and sexual abuse before t... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2022 |
Reihe/Periodikum: | de Koning , R M , Kuzminskaite , E , Vinkers , C H , Giltay , E J & Penninx , B W J H 2022 , ' Childhood trauma and LPS-stimulated inflammation in adulthood : Results from the Netherlands Study of Depression and Anxiety ' , Brain, Behavior, and Immunity , vol. 106 , pp. 21-29 . https://doi.org/10.1016/j.bbi.2022.07.158 |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27232729 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://research.vumc.nl/en/publications/3b67a66c-9473-492a-8bdc-ec9f38c08bab |