Real-world Evidence of the Effects of Novel Treatments for COVID-19 on Mortality:A Nationwide Comparative Cohort Study of Hospitalized Patients in the First, Second, Third, and Fourth Waves in the Netherlands
Background: Large clinical trials on drugs for hospitalized coronavirus disease 2019 (COVID-19) patients have shown significant effects on mortality. There may be a discrepancy with the observed real-world effect. We describe the clinical characteristics and outcomes of hospitalized COVID-19 patients in the Netherlands during 4 pandemic waves and analyze the association of the newly introduced treatments with mortality, intensive care unit (ICU) admission, and discharge alive. Methods: We conducted a nationwide retrospective analysis of hospitalized COVID-19 patients between February 27, 2020,... Mehr ...
Verfasser: |
Slim, Marleen A.
Appelman, Brent
Peters-Sengers, Hessel
Dongelmans, Dave A.
de Keizer, Nicolette F.
Schade, Rogier P.
de Boer, Mark G. J.
Müller, Marcella C. A.
Vlaar, Alexander P. J.
Wiersinga, W. Joost
van Vught, Lonneke A. |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2022 |
Reihe/Periodikum: |
Slim , M A , Appelman , B , Peters-Sengers , H , Dongelmans , D A , de Keizer , N F , Schade , R P , de Boer , M G J , Müller , M C A , Vlaar , A P J , Wiersinga , W J & van Vught , L A 2022 , ' Real-world Evidence of the Effects of Novel Treatments for COVID-19 on Mortality : A Nationwide Comparative Cohort Study of Hospitalized Patients in the First, Second, Third, and Fourth Waves in the Netherlands ' , Open Forum Infectious Diseases , vol. 9 , no. 12 , ofac632 . https://doi.org/10.1093/ofid/ofac632 |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-27232249 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://research.vumc.nl/en/publications/64d55018-d379-4c4e-99c3-1e2304b1a450 |