The Dopaminergic Reward System and Leisure Time Exercise Behavior: A Candidate Allele Study

Purpose. Twin studies provide evidence that genetic influences contribute strongly to individual differences in exercise behavior. We hypothesize that part of this heritability is explained by genetic variation in the dopaminergic reward system. Eight single nucleotide polymorphisms (SNPs in DRD1: rs265981, DRD2: rs6275, rs1800497, DRD3: rs6280, DRD4: rs1800955, DBH: rs1611115, rs2519152, and in COMT: rs4680) and three variable number of tandem repeats (VNTRs in DRD4, upstream of DRD5, and in DAT1) were investigated for an association with regular leisure time exercise behavior. Materials and... Mehr ...

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Verfasser: Huppertz, C.
Bartels, M.
Blokhuis, M.M.
Dolan, C.V.
de Moor, M.H.M.
Abdellaoui, A.
van Beijsterveldt, C.E.M.
Ehli, E.A.
Hottenga, J.J.
Willemsen, G.
Xiao, X.
Scheet, P.
Davies, G.E.
Boomsma, D.I.
Hudziak, J.J.
de Geus, E.J.C.
Dokumenttyp: Artikel
Erscheinungsdatum: 2014
Reihe/Periodikum: Huppertz , C , Bartels , M , Blokhuis , M M , Dolan , C V , de Moor , M H M , Abdellaoui , A , van Beijsterveldt , C E M , Ehli , E A , Hottenga , J J , Willemsen , G , Xiao , X , Scheet , P , Davies , G E , Boomsma , D I , Hudziak , J J & de Geus , E J C 2014 , ' The Dopaminergic Reward System and Leisure Time Exercise Behavior: A Candidate Allele Study ' , Biomed research international , vol. 2014 , 591717 . https://doi.org/10.1155/2014/591717
Schlagwörter: /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_ / name=Netherlands Twin Register (NTR)
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27231731
Datenquelle: BASE; Originalkatalog
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Link(s) : https://research.vu.nl/en/publications/da363ebd-ccbf-411a-9e3d-56faea8b2512