Short communication: Genetic association between schizophrenia and cannabis use
BACKGROUND AND AIM: Previous studies have shown a relationship between schizophrenia and cannabis use. As both traits are substantially heritable, a shared genetic liability could explain the association. We use two recently developed genomics methods to investigate the genetic overlap between schizophrenia and cannabis use. METHODS: Firstly, polygenic risk scores for schizophrenia were created based on summary statistics from the largest schizophrenia genome-wide association (GWA) meta-analysis to date. We analysed the association between these schizophrenia polygenic scores and multiple cann... Mehr ...
Verfasser: |
Verweij, C.J.H.
Abdellaoui, A.
Nivard, Michel G
Sainz Cort, Alberto
Ligthart, L.
Draisma, Harmen H M
Minica, C.C.
Willemsen, G.
Hottenga, J.J.
Boomsma, D.I.
Vink, J.M. |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2017 |
Reihe/Periodikum: |
Verweij , C J H , Abdellaoui , A , Nivard , M G , Sainz Cort , A , Ligthart , L , Draisma , H H M , Minica , C C , International Cannabis Consortium , Willemsen , G , Hottenga , J J , Boomsma , D I & Vink , J M 2017 , ' Short communication: Genetic association between schizophrenia and cannabis use ' , Drug and Alcohol Dependence , vol. 171 , pp. 117-121 . https://doi.org/10.1016/j.drugalcdep.2016.09.022 |
Schlagwörter: |
Journal Article
/ /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR)
/ /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
/ name=SDG 3 - Good Health and Well-being |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-27231236 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://research.vu.nl/en/publications/679969ca-9c4c-425b-856c-22935f60977a |