Effect of Genome and Environment on Metabolic and Inflammatory Profiles

Twin and family studies have established the contribution of genetic factors to variation in metabolic, hematologic and immunological parameters. The majority of these studies analyzed single or combined traits into pre-defined syndromes. In the present study, we explore an alternative multivariate approach in which a broad range of metabolic, hematologic, and immunological traits are analyzed simultaneously to determine the resemblance of monozygotic (MZ) twin pairs, twin-spouse pairs and unrelated, non-cohabiting individuals. A total of 17 participants from the Netherlands Twin Register, inc... Mehr ...

Verfasser: Sirota, M.
Willemsen, G.
Sundar, P.
Pitts, S.J.
Potluri, S.
Prifti, E.
Kennedy, S.H.
Ehrlich, S.D.
Neuteboom, J.
Kluft, C.
Malone, K.E.
Cox, D.R.
de Geus, E.J.C.
Boomsma, D.I.
Dokumenttyp: Artikel
Erscheinungsdatum: 2015
Reihe/Periodikum: Sirota , M , Willemsen , G , Sundar , P , Pitts , S J , Potluri , S , Prifti , E , Kennedy , S H , Ehrlich , S D , Neuteboom , J , Kluft , C , Malone , K E , Cox , D R , de Geus , E J C & Boomsma , D I 2015 , ' Effect of Genome and Environment on Metabolic and Inflammatory Profiles ' , PLoS ONE , vol. 10 , no. 4 , e0120898 , pp. e0120898 . https://doi.org/10.1371/journal.pone.0120898
Schlagwörter: /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_ / name=Netherlands Twin Register (NTR) / /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being / name=SDG 3 - Good Health and Well-being
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27230851
Datenquelle: BASE; Originalkatalog
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Link(s) : https://research.vu.nl/en/publications/26abd31f-1442-47e5-98b2-47c72baa2b6c