Early-life antibiotic use and risk of asthma and eczema:results of a discordant twin study

RATIONALE: Early-life antibiotic use has been associated with development of atopic diseases, but the aetiology remains unclear. To elucidate aetiology, we used a discordant twin design to control for genetic and environmental confounding. METHODS: We conducted a retrospective cohort study in twins (3-10 years) from the Netherlands Twin Register (NTR, n=34 352) and a replication study at age 9 in the Childhood and Adolescent Twin Study in Sweden (CATSS, n=7906). Antibiotic use was recorded at 0-2 years. Doctor diagnosed asthma and eczema were reported by parents when children were 3-12 years i... Mehr ...

Volltext
Verfasser: Slob, Elise M A
Brew, Bronwyn K
Vijverberg, Susanne J H
Kats, Chantal J A R
Longo, Cristina
Pijnenburg, Mariëlle W
van Beijsterveldt, Toos C E M
Dolan, Conor V
Bartels, Meike
Magnusson, Patrick
Lichtenstein, Paul
Gong, Tong
Koppelman, Gerard H
Almqvist, Catarina
Boomsma, Dorret I
Maitland-van der Zee, Anke H
Dokumenttyp: Artikel
Erscheinungsdatum: 2020
Reihe/Periodikum: Slob , E M A , Brew , B K , Vijverberg , S J H , Kats , C J A R , Longo , C , Pijnenburg , M W , van Beijsterveldt , T C E M , Dolan , C V , Bartels , M , Magnusson , P , Lichtenstein , P , Gong , T , Koppelman , G H , Almqvist , C , Boomsma , D I & Maitland-van der Zee , A H 2020 , ' Early-life antibiotic use and risk of asthma and eczema : results of a discordant twin study ' , European Respiratory Journal , vol. 55 , no. 4 , 1902021 , pp. 1-11 . https://doi.org/10.1183/13993003.02021-2019
Schlagwörter: /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_ / name=Netherlands Twin Register (NTR) / /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being / name=SDG 3 - Good Health and Well-being
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27228400
Datenquelle: BASE; Originalkatalog
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Link(s) : https://research.vu.nl/en/publications/08604ab8-3cf4-4e97-b6bd-07d46586f99d