Early-life antibiotic use and risk of attention-deficit hyperactivity disorder and autism spectrum disorder: results of a discordant twin study
Background: Development of the gut-brain axis in early life may be disturbed by antibiotic use. It has been hypothesized that this disturbance may contribute to development of neurodevelopmental disorders, including autism spectrum disorder and attention-deficit hyperactivity disorder. We aimed to assess the association between antibiotic use in early life and the risk of developing attention-deficit hyperactivity disorder or autism spectrum disorder, while controlling for shared genetic and environmental factors in a discordant twin design. Methods: We conducted a cohort study in twins (7–12... Mehr ...
Verfasser: |
Slob, EMA
Brew, BK
Vijverberg, SJH
Dijs, T
van Beijsterveldt, CEM
Koppelman, GH
Bartels, M
Dolan, CV
Larsson, H
Lundström, S
Lichtenstein, P
Gong, T
Maitland-Van der Zee, AH
Kraneveld, AD
Almqvist, C
Boomsma, DI
Haasdyk, Bronwyn Brew |
Dokumenttyp: |
journal article |
Erscheinungsdatum: |
2021 |
Verlag/Hrsg.: |
Oxford University Press (OUP)
|
Schlagwörter: |
Behavioral and Social Science
/ Genetics
/ Clinical Trials and Supportive Activities
/ Prevention
/ Mental Health
/ Brain Disorders
/ Autism
/ Clinical Research
/ Intellectual and Developmental Disabilities (IDD)
/ Pediatric
/ Neurosciences
/ 2 Aetiology
/ 2.3 Psychological
/ social and economic factors
/ 2.1 Biological and endogenous factors
/ Adolescent
/ Anti-Bacterial Agents
/ Attention Deficit Disorder with Hyperactivity
/ Autism Spectrum Disorder
/ Child
/ Preschool
/ Cohort Studies
/ Humans
/ Netherlands
/ Sweden
/ ADHD
/ ASD
/ antibiotics
/ children
/ discordant twin design
/ early life
/ gut-brain axis
/ anzsrc-for: 0104 Statistics
/ anzsrc-for: 1117 Public Health and Health Services |
Sprache: |
unknown |
Permalink: |
https://search.fid-benelux.de/Record/base-27224368 |
Datenquelle: |
BASE;
Originalkatalog |
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BASE |
Link(s) :
|
http://hdl.handle.net/1959.4/unsworks_77340 |