Neurobiological, psychosocial, and behavioral mechanisms mediating associations between physical activity and psychiatric symptoms in youth in the Netherlands

Abstract: IMPORTANCE Understanding the mechanisms by which physical activity is associated with a lower risk of psychiatric symptoms may stimulate the identification of cost-efficient strategies for preventing and treating mental illness at early life stages.OBJECTIVE To examine neurobiological, psychosocial, and behavioral mechanisms that mediate associations of physical activity with psychiatric symptoms in youth by testing an integrated model.DESIGN, SETTING, AND PARTICIPANTS Generation R is an ongoing prospective population-based cohort study collecting data from fetal life until young adu... Mehr ...