This study quantitatively investigates enrolments of international students using data that contains nearly every student in the Netherlands for the years 2016–2019. Using this data, we are able to perform a meso-level analysis where we could investigate the characteristics of higher education institutions (HEIs) and cities in international student mobility. This research contributes to the literature by studying variation between HEIs and by focusing on actual enrolments instead of relying on survey results. Such meso-level studies have thus far been very rare, especially on this scale. Although there are commonalities between types of degrees, we find mixed results for academic and city characteristics, and it appears that academic factors are more important for master students while for bachelor students city characteristics have stronger effects. The effect of having already existing stocks of international students appears to be important for all types of degrees. Aside from differences between bachelor and master students, our findings also suggest that HEIs might directly influence international student flows as this would explain some of our results. Although this study only focuses on the Netherlands, it opens up many avenues for future comparative research on the destination choices of international students and the role of HEIs.