Eight years of experience with vismodegib for advanced and multiple basal cell carcinoma patients in the Netherlands:a retrospective cohort study

BACKGROUND: Vismodegib has been used for the treatment of locally advanced basal cell carcinoma (laBCC) and metastatic BCC (mBCC) since 2011. Most efficacy and safety data are provided by clinical trials. This study evaluates the effectiveness of vismodegib for the treatment of laBCC, mBCC and basal cell nevus syndrome (BCNS) patients, and the tumour characteristics associated with a higher probability of achieving a complete response in the Netherlands. METHODS: A retrospective cohort study that included all patients ≥18 years with histologically proven basal cell carcinoma that received ≥1 d... Mehr ...

Verfasser: Verkouteren, Babette J. A.
Wakkee, Marlies
Reyners, An K. L.
Nelemans, Patty
Aarts, Maureen J. B.
Racz, Emoke
Terra, Jorrit B.
Devriese, Lot A.
Alers, Robert-Jan
Kapiteijn, Ellen
van Doorn, Remco
Bekkenk, Marcel W.
Reinders, Marie G. H. C.
Mosterd, Klara
Dokumenttyp: Artikel
Erscheinungsdatum: 2021
Reihe/Periodikum: Verkouteren , B J A , Wakkee , M , Reyners , A K L , Nelemans , P , Aarts , M J B , Racz , E , Terra , J B , Devriese , L A , Alers , R-J , Kapiteijn , E , van Doorn , R , Bekkenk , M W , Reinders , M G H C & Mosterd , K 2021 , ' Eight years of experience with vismodegib for advanced and multiple basal cell carcinoma patients in the Netherlands : a retrospective cohort study ' , British Journal of Cancer . https://doi.org/10.1038/s41416-020-01220-w
Schlagwörter: EFFICACY / STEVIE / SAFETY
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27210594
Datenquelle: BASE; Originalkatalog
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Link(s) : https://hdl.handle.net/11370/9ac40412-ab22-41d7-bb89-60494ae5c0c4