Real-world outcomes versus clinical trial results of immunotherapy in stage IV non-small cell lung cancer (NSCLC) in the Netherlands
This study aims to assess how clinical outcomes of immunotherapy in real-world (effectiveness) correspond to outcomes in clinical trials (efficacy) and to look into factors that might explain an efficacy-effectiveness (EE) gap. All patients diagnosed with stage IV non-small cell lung cancer (NSCLC) in 2015-2018 in six Dutch large teaching hospitals (Santeon network) were identified and followed-up from date of diagnosis until death or end of data collection. Progression-free survival (PFS) and overall survival (OS) from first-line (1L) pembrolizumab and second-line (2L) nivolumab were compared... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2021 |
Reihe/Periodikum: | Santeon NSCLC Study Group , Cramer-van der Welle , C M , Verschueren , M V , Tonn , M , Peters , B J M , Schramel , F M N H , Klungel , O H , Groen , H J M & van de Garde , E M W 2021 , ' Real-world outcomes versus clinical trial results of immunotherapy in stage IV non-small cell lung cancer (NSCLC) in the Netherlands ' , Scientific Reports , vol. 11 , no. 1 , 6306 . https://doi.org/10.1038/s41598-021-85696-3 |
Schlagwörter: | NIVOLUMAB / DOCETAXEL / POPULATION |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27210323 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://hdl.handle.net/11370/7ade8633-d066-4b06-bd3a-53d40279022c |