Background: The Intergroup 0116 and the MAGIC trials changed clinical practice for resectable gastric cancer in the Western world. In these trials, overall survival improved with post-operative chemoradiotherapy (CRT) and perioperative chemotherapy (CT). Intention-to-treat analysis in the CRITICS trial of post-operative CT or post-operative CRT did not show a survival difference. The current study reports on the per-protocol (PP) analysis of the CRITICS trial. Patients and methods: The CRITICS trial was a randomized, controlled trial in which 788 patients with stage Ib–Iva resectable gastric o... Mehr ...
| Verfasser: |
de Steur, W. O.
van Amelsfoort, R. M.
Hartgrink, H. H.
Putter, H.
Meershoek-Klein Kranenbarg, E.
van Grieken, N. C.T.
van Sandick, J. W.
Claassen, Y. H.M.
Braak, J. P.B.M.
Jansen, E. P.M.
Sikorska, K.
van Tinteren, H.
Walraven, I.
Lind, P.
Nordsmark, M.
van Berge Henegouwen, M. I.
van Laarhoven, H. W.M.
Cats, A.
Verheij, M.
van de Velde, C. J.H. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2021 |
| Reihe/Periodikum: |
de Steur , W O , van Amelsfoort , R M , Hartgrink , H H , Putter , H , Meershoek-Klein Kranenbarg , E , van Grieken , N C T , van Sandick , J W , Claassen , Y H M , Braak , J P B M , Jansen , E P M , Sikorska , K , van Tinteren , H , Walraven , I , Lind , P , Nordsmark , M , van Berge Henegouwen , M I , van Laarhoven , H W M , Cats , A , Verheij , M , van de Velde , C J H & CRITICS investigators 2021 , ' Adjuvant chemotherapy is superior to chemoradiation after D2 surgery for gastric cancer in the per-protocol analysis of the randomized CRITICS trial ' , Annals of Oncology , vol. 32 , no. 3 , pp. 360-367 . https://doi.org/10.1016/j.annonc.2020.11.004 |
| Schlagwörter: |
chemoradiotherapy
/ chemotherapy
/ gastric cancer
/ per-protocol analysis
/ post-operative treatment
/ survival
/ Humans
/ Antineoplastic Combined Chemotherapy Protocols
/ Adjuvant
/ Stomach Neoplasms/drug therapy
/ Sweden
/ Netherlands/epidemiology |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-27208926 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://pure.au.dk/portal/en/publications/13ec5054-3376-4eac-9e44-ea3aff6dff06 |
