Age-specific HPV seroprevalence among young females in The Netherlands

Objectives To obtain insight into the age-specific seroprevalence for human papillomavirus (HPV) 6, 11, 16 and 18 among females before introduction of HPV vaccination in The Netherlands. Methods In a population-based study in The Netherlands, 637 sera of 11–26-year-old females were tested for HPV6/11/16/18 antibodies. Sera were tested using a competitive Luminex assay with neutralising monoclonal antibodies specific for each serotype. Associations between HPV seropositivity, demographics, and sexual behaviour were studied with logistic regression. Seroprevalences were standardised for age and... Mehr ...