Cluster of Cases of Acute Hepatitis Associated with Hepatitis E Virus Infection Acquired in The Netherlands

Increasing evidence suggests that hepatitis E virus (HEV) infection may occur in developed countries and that swine may act as a reservoir. We report a cluster of 2 confirmed cases and 1 presumptive case of hepatitis associated with HEV. The typed strain from 1 case was related to HEV strains found in North America and Europe, and it was also related to a cluster of swine HEV strains found in The Netherlands. Our findings indicate that locally acquired HEV infections in industrialized countries may be overlooked. Routine testing for HEV infection in patients with acute hepatitis in The Netherl... Mehr ...

Verfasser: Widdowson, Marc-Alain
Jaspers, Wim J. M.
van der Poel, Wim H. M.
Verschoor, Froukje
de Roda Husman, Ana Maria
Winter, H. L. J.
Zaaijer, Hans L.
Koopmans, Marion
Dokumenttyp: TEXT
Erscheinungsdatum: 2003
Verlag/Hrsg.: Oxford University Press
Schlagwörter: Major Articles
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27195387
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : http://cid.oxfordjournals.org/cgi/content/short/36/1/29

Increasing evidence suggests that hepatitis E virus (HEV) infection may occur in developed countries and that swine may act as a reservoir. We report a cluster of 2 confirmed cases and 1 presumptive case of hepatitis associated with HEV. The typed strain from 1 case was related to HEV strains found in North America and Europe, and it was also related to a cluster of swine HEV strains found in The Netherlands. Our findings indicate that locally acquired HEV infections in industrialized countries may be overlooked. Routine testing for HEV infection in patients with acute hepatitis in The Netherlands should be considered before a diagnosis of autoimmune hepatitis is reached and steroid therapy is initiated.