Establishing a controlled hookworm human infection (CHHI) model for Africa: A report from the stakeholders meeting held in Lambaréné, Gabon, November 10–11, 2019

Abstract Background Hookworm is a major contributor to worldwide disease burden with over 230 million people infected. It has been identified as one of the Neglected Tropical Diseases that can be controlled and even eliminated through mass drug administration and other effective interventions. Mathematical models have shown that hookworm can only be eliminated via a vaccine. Controlled Hookworm Human Infection (CHHI) models can facilitate rapid development of vaccines and drugs. Methods As a first step towards the establishment of CHHI in Africa, we held a stakeholders meeting in Lamberene, Ga... Mehr ...

Verfasser: Ayodele Alabi
Mosarrof Hussain
Marie-Astrid Hoogerwerf
Christine Ndong Mengome
Moses Egesa
Emmanuella Driciru
Linda J. Wammes
Yvonne C. M. Kruize
Erliyani Sartono
Ayola Akim Adegnika
Peter G. Kremsner
Maria Yazdanbakhsh
Selidji Todagbe Agnandji
Dokumenttyp: Artikel
Erscheinungsdatum: 2021
Reihe/Periodikum: Archives of Public Health, Vol 79, Iss 1, Pp 1-8 (2021)
Verlag/Hrsg.: BMC
Schlagwörter: Controlled human infection model / Necator americanus / Vaccine development / Gabon / The Netherlands / Public aspects of medicine / RA1-1270
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27191811
Datenquelle: BASE; Originalkatalog
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Link(s) : https://doi.org/10.1186/s13690-021-00650-z