Incidence rates of dysvascular lower extremity amputation changes in Northern Netherlands: A comparison of three cohorts of 1991-1992, 2003-2004 and 2012-2013.

OBJECTIVE:To analyze the incidence rates of dysvascular major lower extremity amputations (LEA) in Northern Netherlands in 2012-2013 compared to previous cohorts in 1991-1992 and 2003-2004. DESIGN:Retrospective cohort study. PARTICIPANTS:Adults (N = 343) with first ever dysvascular LEA at ankle disarticulation or more proximal levels. The median age (interquartile range) was 74.2 years (64.5-81.9), 64% were male and 55% had been diagnosed with diabetes mellitus (DM). MAIN OUTCOME MEASURES:Crude and age-standardized incidence rates of major LEA per 100.000 person-years. RESULTS:Crude incidence... Mehr ...