First evidence of Seoul hantavirus in the wild rat population in the Netherlands

We report the first detection of Seoul hantavirus (SEOV)-specific antibodies in the wild brown rat population in the Netherlands. SEOV-reactive antibodies were found in three rats out of 16 in a repeated series of tests including immunofluorescence assay, immunoblot, and enzyme-linked immunosorbent assay. Focus reduction neutralization test confirmed the presence of SEOV-specific antibodies, and reverse-transcription polymerase chain reaction (RT-PCR) confirmed the presence of hantaviral RNA. This discovery follows the recent findings of SEOV infections in wild and pet brown rats and humans in... Mehr ...

Verfasser: Jenny Verner-Carlsson
Mare Lõhmus
Karin Sundström
Tanja M. Strand
Monique Verkerk
Chantal Reusken
Kumiko Yoshimatsu
Jiro Arikawa
Frank van de Goot
Åke Lundkvist
Dokumenttyp: Artikel
Erscheinungsdatum: 2015
Reihe/Periodikum: Infection Ecology & Epidemiology, Vol 5, Iss 0, Pp 1-4 (2015)
Verlag/Hrsg.: Taylor & Francis Group
Schlagwörter: Seoul virus / wildlife diseases / hantavirus / rodent-borne diseases / Infectious and parasitic diseases / RC109-216
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27190626
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://doi.org/10.3402/iee.v5.27215

We report the first detection of Seoul hantavirus (SEOV)-specific antibodies in the wild brown rat population in the Netherlands. SEOV-reactive antibodies were found in three rats out of 16 in a repeated series of tests including immunofluorescence assay, immunoblot, and enzyme-linked immunosorbent assay. Focus reduction neutralization test confirmed the presence of SEOV-specific antibodies, and reverse-transcription polymerase chain reaction (RT-PCR) confirmed the presence of hantaviral RNA. This discovery follows the recent findings of SEOV infections in wild and pet brown rats and humans in England, Wales, France, Belgium, and Sweden, indicating an even higher importance of this hantavirus for public health in large areas of Europe.