Changes in the genomic content of circulating Bordetella pertussis strains isolated from the Netherlands, Sweden, Japan and Australia: adaptive evolution or drift?
Abstract Background Bordetella pertussis is the causative agent of human whooping cough (pertussis) and is particularly severe in infants. Despite worldwide vaccinations, whooping cough remains a public health problem. A significant increase in the incidence of whooping cough has been observed in many countries since the 1990s. Several reasons for the re-emergence of this highly contagious disease have been suggested. A particularly intriguing possibility is based on evidence indicating that pathogen adaptation may play a role in this process. In an attempt to gain insight into the genomic mak... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2010 |
Reihe/Periodikum: | BMC Genomics, Vol 11, Iss 1, p 64 (2010) |
Verlag/Hrsg.: |
BMC
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Schlagwörter: | Biotechnology / TP248.13-248.65 / Genetics / QH426-470 |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27190437 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://doi.org/10.1186/1471-2164-11-64 |