This article deals with the history of the neo-Calvinist movement in France and Italy. The efforts of the Dutch Reformational movement to communicate with French (mainly reformed) Christians are highlighted. A brief overview of the achievements of the few French scholars involved in this development is sketched and their publications are mentioned, together with a few conferences and organisations. Neo-Calvinism reached Italy as well, via the input of French lecturers and publications. The few developments of neo-Calvinism in Italy are recorded as well. Also, the gradual drift towards vantilian and reconstructionist positions (in both countries) is detected and discussed. An evaluation of these developments is provided, together with a few final considerations and questions which should help learning lessons from the past and preparing better strategies for the future.