Effects of population based screening for Chlamydia infections in the Netherlands limited by declining participation rates.

Background A large trial to investigate the effectiveness of population based screening for chlamydia infections was conducted in the Netherlands in 2008-2012. The trial was register based and consisted of four rounds of screening of women and men in the age groups 16-29 years in three regions in the Netherlands. Data were collected on participation rates and positivity rates per round. A modeling study was conducted to project screening effects for various screening strategies into the future. Methods and findings We used a stochastic network simulation model incorporating partnership formati... Mehr ...