The rationale of opportunistic bilateral salpingectomies (OBS) during benign gynaecological and obstetric surgery : a consensus text of the Flemish Society of Obstetrics and Gynaecology (VVOG)

Abstract: Ovarian cancer (OC), is a disease difficult to diagnose in an early stage implicating a poor prognosis. The 5-year overall survival in Belgium has not changed in the last 18 years and remains 44 %. There is no effective screening method (secondary prevention) to detect ovarian cancer at an early stage. Primary prevention of ovarian cancer came in the picture through the paradigm shift that the fallopian tube is often the origin of ovarian cancer and not the ovary itself. Opportunistic bilateral salpingectomy (OBS) during benign gynaecological and obstetric surgery might have the pote... Mehr ...

Verfasser: Tjalma, Wiebren
Bosteels, J.A.
Cooremans, I.
Cosyns, S.
De Greve, M.
De Vree, B.P.
Debruyne, D.
De Jonge, E.T.
Desmedt, E.J., I
Dubois, P.
Faes, T.
Francx, M.
Hamerlyncki, T.
Makar, A.P.
Maryns, A.S.
Michiels, I.
Orye, G.
Platteeuw, L.
Pouseele, B.
Schutyser, V.
Segaert, A.
Stevens, M.
Tomassetti, C.
Trinh, Xuan Bich
Tummers, P.
Van Calenberg, S.G.K.
Van Dam, Peter André
Van Herendael, B.
Vanspauwen, R.
Vergote, I.B.
Verguts, J.
Waity, K.
Weyers, S.
Dokumenttyp: Artikel
Erscheinungsdatum: 2019
Schlagwörter: Human medicine
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27093679
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://hdl.handle.net/10067/1638230151162165141

Abstract: Ovarian cancer (OC), is a disease difficult to diagnose in an early stage implicating a poor prognosis. The 5-year overall survival in Belgium has not changed in the last 18 years and remains 44 %. There is no effective screening method (secondary prevention) to detect ovarian cancer at an early stage. Primary prevention of ovarian cancer came in the picture through the paradigm shift that the fallopian tube is often the origin of ovarian cancer and not the ovary itself. Opportunistic bilateral salpingectomy (OBS) during benign gynaecological and obstetric surgery might have the potential to reduce the risk of ovarian cancer by as much as 65 %. Bilateral risk-reducing salpingectomy during a benign procedure is feasible, safe, appears to have no impact on the ovarian function and seems to be cost effective. The key question is whether we should wait for a RCT or implement OBS directly in our daily practice. Guidelines regarding OBS within our societies are therefore urgently needed. Our recommendation is to inform all women without a child wish, undergoing a benign gynaecological or obstetrical surgical procedure about the pro's and the con's of OBS and advise a bilateral salpingectomy. Furthermore, there is an urgent need for a prospective registry of OBS. The present article is the consensus text of the Flemish Society of Obstetrics and Gynaecology (VVOG) regarding OBS.