Genome wide scan in a Flemish inflammatory bowel disease population: support for the IBD4 locus, population heterogeneity, and epistasis
Background and aims: Genome wide scans in inflammatory bowel disease (IBD) have indicated various susceptibility regions with replication of 16cen ( IBD1 ), 12q ( IBD2 ), 6p ( IBD3 ), 14q11 ( IBD4 ), and 3p21. As no linkage was previously found on IBD regions 3, 7, 12, and 16 in Flemish IBD families, a genome wide scan was performed to detect other susceptibility regions in this population. Methods: A cohort of 149 IBD affected relative pairs, all recruited from the Northern Flemish part of Belgium, were genotyped using microsatellite markers at 12 cM intervals, and analysed by Genehunter non-... Mehr ...
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Dokumenttyp: | TEXT |
Erscheinungsdatum: | 2004 |
Verlag/Hrsg.: |
BMJ Publishing Group Ltd
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Schlagwörter: | Inflammatory bowel disease |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27089107 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://gut.bmj.com/cgi/content/short/53/7/980 |