Congenital leukaemia: the Dutch experience and review of the literature
Summary. We reviewed Dutch patients and those described in the literature with congenital leukaemia in the past 25 years, with the intention to obtain an overview of the characteristics of this rare disease. Among the 117 patients reviewed, acute myeloid leukaemia (AML) was more frequent (64%) than acute lymphoblastic leukaemia (ALL, 21%). Most patients had a high leukaemic cell load with hepatosplenomegaly, leukaemia cutis and hyperleucocytosis. Cytogenetic abnormalities were found in the majority of the patients tested (72%); 11q23 abnormalities were found in less than half of them (42%). Th... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2002 |
Reihe/Periodikum: | British Journal of Haematology ; volume 117, issue 3, page 513-524 ; ISSN 0007-1048 1365-2141 |
Verlag/Hrsg.: |
Wiley
|
Schlagwörter: | Hematology |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27079861 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://dx.doi.org/10.1046/j.1365-2141.2002.03459.x |