Effect of increased convective clearance by on-line hemodiafiltration on all cause and cardiovascular mortality in chronic hemodialysis patients – the Dutch CONvective TRAnsport STudy (CONTRAST): rationale and design of a randomised controlled trial [ISRCTN38365125]

Abstract Background The high incidence of cardiovascular disease in patients with end stage renal disease (ESRD) is related to the accumulation of uremic toxins in the middle and large-middle molecular weight range. As online hemodiafiltration (HDF) removes these molecules more effectively than standard hemodialysis (HD), it has been suggested that online HDF improves survival and cardiovascular outcome. Thus far, no conclusive data of HDF on target organ damage and cardiovascular morbidity and mortality are available. Therefore, the CONvective TRAnsport STudy (CONTRAST) has been initiated. Me... Mehr ...

Verfasser: Penne, E Lars
Blankestijn, Peter J
Bots, Michiel L
van den Dorpel, Marinus A
Grooteman, Muriel P
Nubé, Menso J
van der Tweel, Ingeborg
ter Wee, Piet M
Dokumenttyp: Artikel
Erscheinungsdatum: 2005
Reihe/Periodikum: Current Controlled Trials in Cardiovascular Medicine ; volume 6, issue 1 ; ISSN 1468-6708 1468-6694
Verlag/Hrsg.: Springer Science and Business Media LLC
Schlagwörter: Cardiology and Cardiovascular Medicine
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27078439
Datenquelle: BASE; Originalkatalog
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Link(s) : http://dx.doi.org/10.1186/1468-6708-6-8