Abstract For the first time, geomorphology and archaeology are combined for a 165 km long stretch of the Meuse river, resulting in a geomorphogenetic map (GKM) and a series of archaeological predictive maps (AVM). The maps cover the central part the Meuse valley, located in the province of Limburg between Mook in the north and Eijsden in the south. The area consists of fluvial and aeolian landforms of the Holocene Meuse floodplain and Younger Dryas aged terraces along it, spanning a period of approximately 15,000 years of landscape genesis and human habitation. The GKM more clearly discriminates between map units of Younger Dryas and early Holocene age than in previous mappings of the Meuse valley. The AVM series provide predictive information on the location of sites for four distinct consecutive archaeological periods and four main cultural themes. The maps contribute to a better understanding of landscape processes (fluvial and aeolian geomorphology and the impact of man on river behaviour), and the possibilities for human habitation and land use in prehistoric and historic times.