Common variants underlying cognitive ability: further evidence for association between the SNAP-25 gene and cognition using a family-based study in two independent Dutch cohorts.
The synaptosomal associated protein of 25 kDa (SNAP-25) gene, located on chromosome 20 p12-12p11.2 encodes a presynaptic terminal protein. SNAP-25 is differentially expressed in the brain, and primarily present in the neocortex, hippocampus, anterior thalamic nuclei, substantia nigra and cerebellar granular cells. Recently, a family-based genetic association was reported between variation in intelligence quotient (IQ) phenotypes and two intronic variants on the SNAP-25 gene. The present study is a follow-up association study in two Dutch cohorts of 371 children (mean age 12.4 years) and 391 ad... Mehr ...
| Verfasser: |
Gosso, M.F.
de Geus, E.J.C.
Polderman, T.J.C.
Boomsma, D.I.
Heutink, P.
Posthuma, D. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2008 |
| Reihe/Periodikum: |
Gosso , M F , de Geus , E J C , Polderman , T J C , Boomsma , D I , Heutink , P & Posthuma , D 2008 , ' Common variants underlying cognitive ability: further evidence for association between the SNAP-25 gene and cognition using a family-based study in two independent Dutch cohorts. ' , Genes, Brain and Behavior , vol. 7 , no. 3 , pp. 355-364 . https://doi.org/10.1111/j.1601-183X.2007.00359.x |
| Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-27074772 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vu.nl/en/publications/5fd33b40-7633-459b-8c40-d4c08f2f22c9 |
