Early recovery of CD4 T lymphocytes in children on highly active antiretroviral therapy. Dutch study group for children with HIV infections
Regeneration of CD4+ T lymphocytes has been shown to be thymus-dependent in bone marrow transplant recipients and after intensive chemotherapy. The rate of CD4+ T cell regeneration is correlated positively with enlargement of the thymus, as shown on radiographs, and higher rates of CD4+ T lymphocyte regeneration were observed in children as compared with adults, consistent with thymic function diminishing with age. We hypothesized that in HIV infected patients CD4+ T cell recovery during highly active antiretroviral therapy (HAART) may also be thymus dependent. Therefore, repopulation of naive... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 1998 |
Schlagwörter: | Biologie / CD4 / CD8 / pediatrics / antiretroviral therapy / immune reconstitution |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27070237 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://dspace.library.uu.nl/handle/1874/8058 |