Locally Advanced Pancreatic Cancer: Exploring treatment strategies

With a worldwide incidence of approximately 496,000 new cases and 466,000 deaths in 2020, pancreatic cancer is among the most deadliest of cancers. The majority of patients present with an advanced stage of cancer at diagnosis. This includes 30-40% of patients with locally advanced pancreatic cancer (LAPC), due to extensive perivascular tumor infiltration without distant metastases. This thesis evaluates treatment strategies and clinical outcomes in patients with locally advanced pancreatic cancer (LAPC) in current clinical practice, investigates tools for selecting patients who will benefit c... Mehr ...