Resilience in refugee and Dutch adolescents: Genetic variability in the corticotropin releasing hormone receptor 1
Relationships between the corticotropin-releasing hormone receptor 1 (CRHR1) [rs878886] and serotonin transporter promoter polymorphism (5-HTTLPR), with resilience and satisfaction with life were examined in 172 adolescents; 70 refugee adolescents living in the Netherlands and 102 non-refugee (Dutch) adolescents. Genetic variation in the CRHR1 was related with self-reported resilience and satisfaction with life, while the 5-HTTLPR polymorphism was not. These findings did not depend on being a refugee or a non-refugee (Dutch) adolescent and did hold after accounting for age, number of exposures... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2017 |
Schlagwörter: | Resilience / Adolescent / Refugee / Corticotropin-releasing hormone receptor 1 / rs878886 / 5-HTTLPR / Genetic / Taverne |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27068672 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://dspace.library.uu.nl/handle/1874/353383 |
Relationships between the corticotropin-releasing hormone receptor 1 (CRHR1) [rs878886] and serotonin transporter promoter polymorphism (5-HTTLPR), with resilience and satisfaction with life were examined in 172 adolescents; 70 refugee adolescents living in the Netherlands and 102 non-refugee (Dutch) adolescents. Genetic variation in the CRHR1 was related with self-reported resilience and satisfaction with life, while the 5-HTTLPR polymorphism was not. These findings did not depend on being a refugee or a non-refugee (Dutch) adolescent and did hold after accounting for age, number of exposures to potentially traumatic events and gender. This implies that adolescents who are G-allele carriers of CRHR1 (rs878886) might be more susceptible to mental health problems following trauma, further suggesting innate differences in CRHR1 as a factor in resilience.