Long-term exposure to fine particulate matter, lung function and cognitive performance: A prospective Dutch cohort study on the underlying routes.

Exposure to fine particulate matter and black carbon is related to cognitive impairment and poor lung function, but less is known about the routes taken by different types of air pollutants to affect cognition.We tested two possible routes of fine particulate matter (PM2.5) and black carbon (BC) in impairing cognition, and evaluated their importance: a direct route over the olfactory nerve or the blood stream, and an indirect route over the lung.We used longitudinal observational data for 49,705 people aged 18+ from 2006 to 2015 from the Dutch Lifelines cohort study. By linking current home ad... Mehr ...

Verfasser: Aretz, Benjamin
Janssen, Fanny
Vonk, Judith M
Heneka, Michael T
Boezen, H Marike
Doblhammer-Reiter, Gabriele
Dokumenttyp: Artikel
Erscheinungsdatum: 2021
Verlag/Hrsg.: Elsevier
Schlagwörter: info:eu-repo/classification/ddc/610 / Air Pollutants: analysis / Air Pollutants: toxicity / Air Pollution: adverse effects / Air Pollution: analysis / Cognition / Cohort Studies / Environmental Exposure: adverse effects / Environmental Exposure: analysis / Forced Expiratory Volume / Humans / Lung / Particulate Matter: analysis / Particulate Matter: toxicity / Prospective Studies / Black carbon / Cognitive performance / Fine particulate matter / Lung function / Mediation analysis / Pathways
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27022384
Datenquelle: BASE; Originalkatalog
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Link(s) : https://pub.dzne.de/record/155657