Study protocol of the DUtch PARkinson Cohort (DUPARC): a prospective, observational study of de novo Parkinson’s disease patients for the identification and validation of biomarkers for Parkinson’s disease subtypes, progression and pathophysiology
Abstract Background Parkinson’s Disease (PD) is a heterogeneous, progressive neurodegenerative disorder which is characterized by a variety of motor and non-motor symptoms. To date, no disease modifying treatment for PD exists. Here, the study protocol of the Dutch Parkinson Cohort (DUPARC) is described. DUPARC is a longitudinal cohort study aimed at deeply phenotyping de novo PD patients who are treatment-naïve at baseline, to discover and validate biomarkers for PD progression, subtypes and pathophysiology. Methods/design DUPARC is a prospective cohort study in which 150 de novo PD subjects... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2020 |
Reihe/Periodikum: | BMC Neurology, Vol 20, Iss 1, Pp 1-11 (2020) |
Verlag/Hrsg.: |
BMC
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Schlagwörter: | Parkinson disease / Neurodegenerative diseases / Observational study / Longitudinal studies / Biomarkers / Neuropsychology / Neurology. Diseases of the nervous system / RC346-429 |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27022149 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://doi.org/10.1186/s12883-020-01811-3 |