Cross-border dissemination of methicillin-resistant Staphylococcus aureus, Euregio Meuse-Rhin region

Because the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) differs among the 3 countries forming the Euregio Meuse-Rhin (EMR) region (Belgium, Germany, and the Netherlands), cross-border healthcare requires information about the spread of MRSA in the EMR. We investigated the emergence, dissemination, and diversity of MRSA clones in the EMR by using several typing methods. MRSA associated with clonal complexes 5, 8, 30, and 45 was disseminated throughout the EMR. Dutch isolates, mainly associated with sequence types (ST) ST5-MRSA-II, ST5-MRSA-IV, ST8-MRSA-IV, and ST45-MSRA-IV... Mehr ...

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Verfasser: Deurenberg, Ruud H
Nulens, Eric
Valvatne, Havard
Sebastian, Silvie
Driessen, Christel
Craeghs, Jos
De Brauwer, Els
Heising, Bernhard
Kraat, Yvette J
Riebe, Joachim
Stals, Frans S
Trienekens, Thera A
Scheres, Jacques
Friedrich, Alexander W
van Tiel, Frank H
Beisser, Patrick S
Stobberingh, Ellen E
Dokumenttyp: Artikel
Erscheinungsdatum: 2009
Reihe/Periodikum: Deurenberg , R H , Nulens , E , Valvatne , H , Sebastian , S , Driessen , C , Craeghs , J , De Brauwer , E , Heising , B , Kraat , Y J , Riebe , J , Stals , F S , Trienekens , T A , Scheres , J , Friedrich , A W , van Tiel , F H , Beisser , P S & Stobberingh , E E 2009 , ' Cross-border dissemination of methicillin-resistant Staphylococcus aureus, Euregio Meuse-Rhin region ' , Emerging Infectious Diseases , vol. 15 , no. 5 , pp. 727-734 . https://doi.org/10.3201/eid1505.071618
Schlagwörter: Anti-Bacterial Agents / Bacterial Proteins / Belgium / Cloning / Molecular / Community-Acquired Infections / Cross Infection / Drug Resistance / Bacterial / Germany / Humans / Methicillin-Resistant Staphylococcus aureus / Microbial Sensitivity Tests / Netherlands / Polymerase Chain Reaction / Prevalence / Staphylococcal Infections / Virulence Factors / CASSETTE CHROMOSOME MEC / PANTON-VALENTINE LEUKOCIDIN / MULTIPLEX PCR / RAPID IDENTIFICATION / LEUCOCIDIN GENES / ACQUIRED STRAINS / EVOLUTION / VARIANTS / CLONES / LABARATORIES
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26979688
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://hdl.handle.net/11370/924baff2-0db0-41ae-8a7b-257619f3e815

Because the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) differs among the 3 countries forming the Euregio Meuse-Rhin (EMR) region (Belgium, Germany, and the Netherlands), cross-border healthcare requires information about the spread of MRSA in the EMR. We investigated the emergence, dissemination, and diversity of MRSA clones in the EMR by using several typing methods. MRSA associated with clonal complexes 5, 8, 30, and 45 was disseminated throughout the EMR. Dutch isolates, mainly associated with sequence types (ST) ST5-MRSA-II, ST5-MRSA-IV, ST8-MRSA-IV, and ST45-MSRA-IV had a more diverse genetic background than the isolates from Belgium and Germany, associated with ST45-MRSA-IV and ST5-MRSA-II, respectively. MRSA associated with pigs (ST398-MRSA-IV/V) was found in the Dutch area of the EMR. Five percent of the MRSA isolates harbored Panton-Valentine leukocidin and were classified as community-associated MRSA associated with ST1, 8, 30, 80, and 89.