Assessment of presumed small-molecule ligands of telomeric i-DNA by biolayer interferometry (BLI)

International audience ; Biolayer interferometry and circular dichroism spectroscopy were used to investigate the interaction between previously reported i-motif DNA ligands and folded or unfolded i-DNA in acidic (pH 5.5) and near-neutral (pH 6.5) conditions.

Verfasser: Bonnet, Hugues
Morel, Maéva
Devaux, Alexandre
Boissieras, Joseph
Granzhan, Anton
Elias, Benjamin
Lavergne, Thomas
Dejeu, Jérôme
Defrancq, Eric
Dokumenttyp: Artikel
Erscheinungsdatum: 2022
Verlag/Hrsg.: HAL CCSD
Schlagwörter: (Belgium) Electronic Supplementary Information (ESI) available: sensorgrams / Langmuir isotherm / experimental details / CD analysis / calculation / [CHIM.ANAL]Chemical Sciences/Analytical chemistry / [SDV]Life Sciences [q-bio]
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26966974
Datenquelle: BASE; Originalkatalog
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Link(s) : https://hal.archives-ouvertes.fr/hal-03632613