Circulating adrenomedullin estimates survival and reversibility of organ failure in sepsis: the prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock-1 (AdrenOSS-1) study
Background: Adrenomedullin (ADM) regulates vascular tone and endothelial permeability during sepsis. Levels of circulating biologically active ADM (bio-ADM) show an inverse relationship with blood pressure and a direct relationship with vasopressor requirement. In the present prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock 1 (, AdrenOSS-1) study, we assessed relationships between circulating bio-ADM during the initial intensive care unit (ICU) stay and short-term outcome in order to eventually design a biomarker-guided randomized controlled trial.... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2018 |
Verlag/Hrsg.: |
BioMed Central Ltd.
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Schlagwörter: | Biomarker / Outcome / Sepsis-2 / Sepsis-3 / Adrenomedullin / Aged / Belgium / Chi-Square Distribution / Female / France / Germany / Hospital Mortality / Hospitalization / Human / Intensive Care Unit / Italy / Length of Stay / Male / Middle Aged / Multiple Organ Failure / Netherland / Patient Outcome Assessment / Proportional Hazards Model / Prospective Studie / Sepsi / Survival Analysis |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26965510 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://hdl.handle.net/11573/1307718 |