Full-genome next-generation sequencing of hepatitis C virus to assess the accuracy of genotyping by the commercial assay LiPA and the prevalence of resistance-associated substitutions in a Belgian cohort

Funding Information: This work and KTC were supported by grants from the Fonds voor Wetenschappelijk Onderzoek Vlaanderen (FWO) ( G069214 , G0B2317N , 1S38819N ). LC acknowledges FWO travel grant for a research visit at University of Oxford ( V431117N ). The authors thank the staff in Oxford in their support of the laboratory work and the donation of the probes used for enrichment of HCV. Publisher Copyright: © 2022 Elsevier B.V. ; Background: Although most currently used regimens for Hepatitis C virus (HCV) infections can be initiated without prior knowledge of genotype and subtype, genotypin... Mehr ...

Verfasser: Christensen, Kasper T.
Pierard, Florian
Beuselinck, Kurt
Bonsall, David
Bowden, Rory
Lagrou, Katrien
Nevens, Frederik
Schrooten, Yoeri
Simmonds, Peter
Vandamme, Anne Mieke
Van Wijngaerden, Eric
Dierckx, Tim
Cuypers, Lize
Van Laethem, Kristel
Dokumenttyp: Artikel
Erscheinungsdatum: 2022
Schlagwörter: Antiviral resistance / Full genome / Hepatitis C virus / LiPA / Next-generation sequencing / Treatment failure / QR355 Virology / R Medicine / Virology / Infectious Diseases / Applied Microbiology and Biotechnology / SDG 3 - Good Health and Well-being / SDG 9 - Industry / Innovation / and Infrastructure
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26925908
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : http://hdl.handle.net/10362/147814