Multivariate Plackett-Dale inference to study the inheritance of longevity in a Belgian village

We consider a Plackett-Dale model to study familial transmittance of longevity. We focus the analysis on associations between mother, father and first child, and therefore we work with family clusters of equal size. We propose a series of tests to perform inferences on the model parameters. The methodology is applied to a demographic database of a Flemish village (18th-20th century). The main substantial conclusion is that familial transmission happens mainly via the mother. We explore the impact of such other factors as censoring, gender effect, age at death, etc. This paper complements the r... Mehr ...

Verfasser: Tibaldi, Fabian
Van de Putte, Bart
Geys, Helena
Molenberghs, Geert
Matthijs, Koen
Vlietinck, Robert
Dokumenttyp: conferenceObject
Erscheinungsdatum: 2003
Schlagwörter: Epidemiology / Multivariate data / Categorical data / Plackett-Dale model / multivariate survival model / pseudo-likelihood inference / familial clustering / correlation
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26918276
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : http://hdl.handle.net/1942/466

We consider a Plackett-Dale model to study familial transmittance of longevity. We focus the analysis on associations between mother, father and first child, and therefore we work with family clusters of equal size. We propose a series of tests to perform inferences on the model parameters. The methodology is applied to a demographic database of a Flemish village (18th-20th century). The main substantial conclusion is that familial transmission happens mainly via the mother. We explore the impact of such other factors as censoring, gender effect, age at death, etc. This paper complements the results of Matthijs et al. (2002) and suggests further analyses to better understand the precise mechanisms behind these associations. ; The first author wish to thank “Bijzonder Onderzoeksfonds” of the Limburgs Universitair Centrum. The second author thanks to FWO-Vlaanderen. We acknowledge support from Interuniversity Attraction Poles Programme P5/24-Belgian State-Federal Office for Scientific, Technical and Cultural Affairs.