Spontaneous essential hypertension in the non‐human primate Chlorocebus aethiops sabaeus , the African green monkey (1136.16)

Current models of essential hypertension have limited comparisons to humans due to differences in posture and periods of activity. The annual cycle of spontaneous hypertension in male Chlorocebus aethiops sabaeus was assessed in an outbred research colony. Using plethysmography, systolic (SBP) and diastolic blood pressures (DBP) of adult male African Green, or vervet, monkeys (n=163) were measured in May/June after ketamine sedation (~10‐15mg/kg). Blood pressure phenotypes were characterized as hypertensive (HT: SBP 蠅 140mmHg) or normotensive (NT: SBP 蠄 120mmHg). SBP and DBP identified 33% (n=... Mehr ...