Disease burden in primary sclerosing cholangitis in the Netherlands: A long‐term follow‐up study

Abstract Background & Aims Primary sclerosing cholangitis (PSC) is a progressive, cholestatic liver disease which greatly impacts the lives of individuals. Burden of disease due to shortened life expectancy and impaired quality of life is ill‐described. The aim of this study was to assess long‐term disease burden in a large population‐based registry with regard to survival, clinical course, quality adjusted life years (QALYs), medical consumption and work productivity loss. Methods All PSC patients living in a geographically defined area covering ~50% of the Netherlands were included, toge... Mehr ...