European experience with the Afirma Gene Expression Classifier for indeterminate thyroid nodules: A clinical utility study in the Netherlands
Abstract Background The Gene Expression Classifier (GEC) and Genomic Sequencing Classifier (GSC) were developed to improve risk stratification of indeterminate nodules. Our aim was to assess the clinical utility in a European population with restrictive diagnostic workup. Methods Clinical utility of the GEC was assessed in a prospective multicenter cohort of 68 indeterminate nodules. Diagnostic surgical rates for Bethesda III and IV nodules were compared to a historical cohort of 171 indeterminate nodules. Samples were post hoc tested with the GSC. Results The GEC classified 26% as benign. Sur... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2023 |
Reihe/Periodikum: | Head & Neck ; volume 45, issue 9, page 2227-2236 ; ISSN 1043-3074 1097-0347 |
Verlag/Hrsg.: |
Wiley
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Schlagwörter: | Otorhinolaryngology |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26850942 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://dx.doi.org/10.1002/hed.27472 |