Cost-effectiveness of procalcitonin testing to guide antibiotic treatment duration in critically ill patients: results from a randomised controlled multicentre trial in the Netherlands

BACKGROUND: Procalcitonin (PCT) testing can help in safely reducing antibiotic treatment duration in intensive care patients with sepsis. However, the cost-effectiveness of such PCT guidance is not yet known. METHODS: A trial-based analysis was performed to estimate the cost-effectiveness of PCT guidance compared with standard of care (without PCT guidance). Patient-level data were used from the SAPS trial in which 1546 patients were randomised. This trial was performed in the Netherlands, which is a country with, on average, low antibiotic use and a short duration of hospital stay. As quality... Mehr ...

Verfasser: Kip, Michelle M. A.
van Oers, Jos A.
Shajiei, Arezoo
Beishuizen, Albertus
Berghuis, A. M. Sofie
Girbes, Armand R.
de Jong, Evelien
de Lange, Dylan W.
Nijsten, Maarten W. N.
IJzerman, Maarten J.
Koffijberg, Hendrik
Kusters, Ron
Dokumenttyp: Artikel
Erscheinungsdatum: 2018
Reihe/Periodikum: Kip , M M A , van Oers , J A , Shajiei , A , Beishuizen , A , Berghuis , A M S , Girbes , A R , de Jong , E , de Lange , D W , Nijsten , M W N , IJzerman , M J , Koffijberg , H & Kusters , R 2018 , ' Cost-effectiveness of procalcitonin testing to guide antibiotic treatment duration in critically ill patients: results from a randomised controlled multicentre trial in the Netherlands ' , Critical Care , vol. 22 , no. 1 , pp. 293 . https://doi.org/10.1186/s13054-018-2234-3
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26846211
Datenquelle: BASE; Originalkatalog
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Link(s) : https://research.vumc.nl/en/publications/e1aa3b7b-c36d-4733-9147-3b885f7e65fa