Real-world Data of Nivolumab for Patients With Advanced Renal Cell Carcinoma in the Netherlands:An Analysis of Toxicity, Efficacy, and Predictive Markers
Background: Nivolumab, a programmed death 1 inhibitor, has been approved as second-line treatment for advanced renal cell carcinoma (RCC) in Europe since 2016. We investigated the toxicity and efficacy of nivolumab as well as potential predictive biomarkers in the Dutch population. Patients and Methods: This was a retrospective, multicenter study of the Dutch national registry of nivolumab for the treatment of advanced RCC. The main outcome parameters included toxicity, objective response rate (ORR), overall survival (OS), progression-free survival (PFS), time to progression (TTP), and time to... Mehr ...
| Verfasser: |
Verhaart, Saskia Lisa
Abu-Ghanem, Yasmin
Mulder, Sasja F.
Oosting, Sjoukje
Van Der Veldt, Astrid
Osanto, Susanne
Aarts, Maureen J.B.
Houtsma, Danny
Peters, Frank P.J.
Groenewegen, Gerard
Van Herpen, Carla M.L.
Pronk, Loes M.
Tascilar, Metin
Hamberg, Paul
Los, Maartje
Vreugdenhil, Gerard
Polee, Marco
Ten Tije, Albert J.
Haanen, John B.A.G.
Bex, Axel
van den Eertwegh, Alfonsus J. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2021 |
| Reihe/Periodikum: |
Verhaart , S L , Abu-Ghanem , Y , Mulder , S F , Oosting , S , Van Der Veldt , A , Osanto , S , Aarts , M J B , Houtsma , D , Peters , F P J , Groenewegen , G , Van Herpen , C M L , Pronk , L M , Tascilar , M , Hamberg , P , Los , M , Vreugdenhil , G , Polee , M , Ten Tije , A J , Haanen , J B A G , Bex , A & van den Eertwegh , A J 2021 , ' Real-world Data of Nivolumab for Patients With Advanced Renal Cell Carcinoma in the Netherlands : An Analysis of Toxicity, Efficacy, and Predictive Markers ' , Clinical Genitourinary Cancer , vol. 19 , no. 3 , pp. 274.e1-274.e16 . https://doi.org/10.1016/j.clgc.2020.10.003 |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26846100 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
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https://research.vumc.nl/en/publications/b0b0a3b1-1b3b-401b-8548-f3f47f030a43 |
