Symptomatic Skeletal Events and the Use of Bone Health Agents in a Real-World Treated Metastatic Castration Resistant Prostate Cancer Population:Results From the CAPRI-Study in the Netherlands

Background: Patients with metastatic castration resistant prostate cancer (mCRPC) are at risk of symptomatic skeletal events (SSE). Bone health agents (BHA, ie bisphosphonates and denosumab) and new life-prolonging drugs (LPDs) can delay SSEs. The aim of this study is to investigate the use of BHAs in relation to SSEs in treated real-world mCRPC population. Patients and Methods: We included patients from the CAPRI registry who were treated with at least one LPD and diagnosed with bone metastases prior to the start of first LPD (LPD1). Outcomes were SSEs (external beam radiation therapy (EBRT)... Mehr ...

Verfasser: Kuppen, Malou C. P.
Westgeest, Hans M.
van den Eertwegh, Alfons J. M.
van Moorselaar, Reindert J. A.
van Oort, Inge M.
Tascilar, Metin
Mehra, Niven
Lavalaye, Jules
Somford, Diederik M.
Aben, Katja K. H.
Bergman, Andre M.
de Wit, Ronald
van den Bergh, A. C. M. (Fons)
de Groot, Carin A. Uyl-
Gerritsen, Winald R.
Dokumenttyp: Artikel
Erscheinungsdatum: 2022
Reihe/Periodikum: Kuppen , M C P , Westgeest , H M , van den Eertwegh , A J M , van Moorselaar , R J A , van Oort , I M , Tascilar , M , Mehra , N , Lavalaye , J , Somford , D M , Aben , K K H , Bergman , A M , de Wit , R , van den Bergh , A C M , de Groot , C A U & Gerritsen , W R 2022 , ' Symptomatic Skeletal Events and the Use of Bone Health Agents in a Real-World Treated Metastatic Castration Resistant Prostate Cancer Population : Results From the CAPRI-Study in the Netherlands ' , Clinical Genitourinary Cancer , vol. 20 , no. 1 , pp. 43-52 . https://doi.org/10.1016/j.clgc.2021.10.008
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26845867
Datenquelle: BASE; Originalkatalog
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Link(s) : https://research.vumc.nl/en/publications/5079046b-670a-4602-91e1-d96c3ce705f6