Increased transmissibility of SARS-CoV-2 alpha variant (B.1.1.7) in children:three large primary school outbreaks revealed by whole genome sequencing in the Netherlands

Background: Variant of concern (VOC) SARS-CoV-2 alpha variant (B.1.1.7) was the dominant strain in the Netherlands between March 2021–June 2021. We describe three primary school outbreaks due to the alpha variant using whole genome sequencing with evidence of large-scale transmission among children, teachers and their household contacts. Method: All outbreaks described were investigated by the South Limburg Public Health Service, the Netherlands. A case was defined as an individual with a real-time polymerase chain reaction test or antigen test positive for SARS-CoV-2. Whole genome sequencing... Mehr ...

Verfasser: Gorgels, Koen M. F.
van Alphen, Lieke B.
van der Veer, Brian M. J. W.
Hackert, Volker H.
Hensels, Audrey Y. J.
Heijer, Casper D. J. den
Dingemans, Jozef
Savelkoul, Paul H. M.
Hoebe, Christian J. P. A.
Dokumenttyp: Artikel
Erscheinungsdatum: 2022
Reihe/Periodikum: Gorgels , K M F , van Alphen , L B , van der Veer , B M J W , Hackert , V H , Hensels , A Y J , Heijer , C D J D , Dingemans , J , Savelkoul , P H M & Hoebe , C J P A 2022 , ' Increased transmissibility of SARS-CoV-2 alpha variant (B.1.1.7) in children : three large primary school outbreaks revealed by whole genome sequencing in the Netherlands ' , BMC Infectious Diseases , vol. 22 , no. 1 , 713 . https://doi.org/10.1186/s12879-022-07623-9
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26845635
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://research.vumc.nl/en/publications/1887f792-5011-43ef-ad64-60c3c82a093c