A 5-single nucleotide polymorphism (SNP) set has been associated with general cognitive ability in 5000 7-year-old children from the Twins Early Development Study (TEDS). Four of these SNPs were identified through a 10K microarray analysis and one was identified through a targeted analysis of brain-expressed genes. The present study tested this association with general cognitive ability in six population samples of varying size and age from Australia, the UK (Scotland and England) and the Netherlands. Results from the largest sample (N=1310) approached significance (P = 0.06) in the direction... Mehr ...
Verfasser: |
Luciano, M.
Lind, P.A.
Deary, I.J.
Payton, A.
Posthuma, D.
Butcher, L.M.
Bochdanovits, Z.
Whalley, L.J.
Visscher, P.M.
Harris, S.E.
Polderman, T.J.C.
Davis, O.S.P.
Wright, M.J.
Starr, J.M.
de Geus, E.J.C.
Bates, T.C.
Montgomery, GW
Boomsma, D.I.
Martin, N.G.
Plomin, R. |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2008 |
Reihe/Periodikum: |
Luciano , M , Lind , P A , Deary , I J , Payton , A , Posthuma , D , Butcher , L M , Bochdanovits , Z , Whalley , L J , Visscher , P M , Harris , S E , Polderman , T J C , Davis , O S P , Wright , M J , Starr , J M , de Geus , E J C , Bates , T C , Montgomery , GW , Boomsma , D I , Martin , N G & Plomin , R 2008 , ' Testing replication of a 5-SNP set for general cognitive ability in six population samples. ' , European Journal of Human Genetics , vol. 16 , no. 11 , pp. 1388-1395 . https://doi.org/10.1038/ejhg.2008.100 |
Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-26845385 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://research.vu.nl/en/publications/ead46e4a-14dc-40d5-b2ad-1c6e92a5788c |