Sexual dimorphism in cortisol metabolism throughout pubertal development:a longitudinal study
OBJECTIVE: Sex differences in disease susceptibility might be explained by sexual dimorphism in hypothalamic-pituitary-adrenal axis activity, which has been postulated to emerge during puberty. However, studies conducted thus far lacked an assessment of Tanner pubertal stage. This study aimed to assess the contribution of pubertal development to sexual dimorphism in cortisol production and metabolism. METHODS: Participants (n=218), were enrolled from a population-based Netherlands Twin Register. At the ages of 9, 12 and 17 years Tanner pubertal stage was assessed, and early-morning urine sampl... Mehr ...
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| Dokumenttyp: | Artikel |
| Erscheinungsdatum: | 2020 |
| Reihe/Periodikum: | van Keulen , B J , Dolan , C V , van der Voorn , B , Andrew , R , Walker , B R , Hulshoff Poll , H , Boomsma , D I , Rotteveel , J & Finken , M J J 2020 , ' Sexual dimorphism in cortisol metabolism throughout pubertal development : a longitudinal study ' , Endocrine Connections , vol. 9 , no. 6 , pp. 542-551 . https://doi.org/10.1530/EC-20-0123 |
| Schlagwörter: | /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_ / name=Netherlands Twin Register (NTR) |
| Sprache: | Englisch |
| Permalink: | https://search.fid-benelux.de/Record/base-26845377 |
| Datenquelle: | BASE; Originalkatalog |
| Powered By: | BASE |
| Link(s) : | https://research.vu.nl/en/publications/e9ac142b-6066-4e5b-9e38-c5f58c9bd62a |
