Dizygotic twinning is not associated with methylenetetrahydrofolate reductase haplotypes
Background: Folate metabolism is critical to embryonic development, influencing neural tube defects (NTD) and recurrent early pregnancy loss. Polymorphisms in 5,10-methylenetetrahydrofolate reductase (MTHFR) have been associated with dizygotic (DZ) twinning through pregnancy loss. Methods: The C677T and A1298C polymorphisms in MTHFR were genotyped in 258 Australasian families (1016 individuals) and 118 Dutch families (462 individuals) of mothers of DZ twins and a population sample of 462 adolescent twin families (1861 individuals). Haplotypes were constructed from the alleles, and transmission... Mehr ...
Verfasser: |
Montgomery, GW
Zhao, Z.Z.
Morley, K.I.
Marsh, A.J.
Boomsma, D.I.
Martin, N.G.
Duffy, DL |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2003 |
Reihe/Periodikum: |
Montgomery , GW , Zhao , Z Z , Morley , K I , Marsh , A J , Boomsma , D I , Martin , N G & Duffy , DL 2003 , ' Dizygotic twinning is not associated with methylenetetrahydrofolate reductase haplotypes ' , Human Reproduction , vol. 18 , no. 11 , pp. 2460-2464 . https://doi.org/10.1093/humrep/deg441 |
Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR)
/ /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
/ name=SDG 3 - Good Health and Well-being |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-26845324 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://research.vu.nl/en/publications/e273b900-a1e7-4784-a137-f815d3f742da |