DNA methylation signatures of breastfeeding in buccal cells collected in mid-childhood
Breastfeeding has long-term benefits for children that may be mediated via the epigenome. This pathway has been hypothesized, but the number of empirical studies in humans is small and mostly done by using peripheral blood as the DNA source. We performed an epigenome-wide association study (EWAS) in buccal cells collected around age nine (mean = 9.5) from 1006 twins recruited by the Netherlands Twin Register (NTR). An age-stratified analysis examined if effects attenuate with age (median split at 10 years; n<10 = 517, mean age = 7.9; n>10 = 489, mean age = 11.2). We performed replication... Mehr ...
Verfasser: |
Odintsova, Veronika V.
Hagenbeek, Fiona A.
Suderman, Matthew
Caramaschi, Doretta
van Beijsterveldt, Catharina E.M.
Kallsen, Noah A.
Ehli, Erik A.
Davies, Gareth E.
Sukhikh, Gennady T.
Fanos, Vassilios
Relton, Caroline
Bartels, Meike
Boomsma, Dorret I.
van Dongen, Jenny |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2019 |
Reihe/Periodikum: |
Odintsova , V V , Hagenbeek , F A , Suderman , M , Caramaschi , D , van Beijsterveldt , C E M , Kallsen , N A , Ehli , E A , Davies , G E , Sukhikh , G T , Fanos , V , Relton , C , Bartels , M , Boomsma , D I & van Dongen , J 2019 , ' DNA methylation signatures of breastfeeding in buccal cells collected in mid-childhood ' , Nutrients , vol. 11 , no. 11 , 2804 , pp. 1-26 . https://doi.org/10.3390/nu11112804 |
Schlagwörter: |
ALSPAC
/ Breastfeeding
/ DNA methylation
/ EPIC
/ EWAS
/ NTR
/ Twins
/ /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-26844809 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://research.vu.nl/en/publications/a500316d-9f5c-4188-9481-24b7ef608282 |